How does the test work?

Cancerous tumors can form in the ducts of the pancreas and can start to grow out of control. When these tumor cells die, fragments of the tumor cell’s DNA end up circulating in the person’s blood. Utilizing patented technology, the test works by being able to ‘catch’ these DNA signals in the blood that are specific to pancreatic cancer.

This cutting-edge technique is also effective in catching the signals when very few DNA tumor fragments are present. This means the test is able to accurately detect early stages of pancreatic cancer (pancreatic ductal adenocarcinoma – PDAC) even when a person may not yet be experiencing any noticeable symptoms of the cancer.

Facts about Pancreatic Cancer

Despite improvements in treatment options, survival rates for pancreatic cancer continue to be low, in part because pancreatic cancer does not usually exhibit any clear symptoms until it has advanced and spread beyond the pancreas.

Further limiting the ability of doctors to find pancreatic cancer early is the fact that symptoms of pancreatic cancer can be hard to distinguish from other digestive issues.

The good news is that when pancreatic cancer is detected in its early stages, it can be effectively treated through surgery and other techniques.

Who is most at Risk?

There are a number of important risk factors that can help to determine if a person has an elevated risk to develop pancreatic cancer.

A person should consider getting the test if they:


Have one or more 1st Degree Relative with pancreatic cancer, breast cancer, ovarian cancer, prostate cancer, familiar melanoma, or colon cancer


Have experienced unexpected weight loss or prolonged abdominal pain, nausea, or vomiting


Have been diagnosed with chronic pancreatitis or other perplexing GI conditions


Are over 50 and have been diagnosed with new onset diabetes (type 2)

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Symptoms of Pancreatic Cancer


It’s also important to be aware of the other symptoms of pancreatic cancer. Please make sure to notify your doctor or healthcare provider right away if you are experiencing any of the following:

  • * Pain in the abdomen or middle of the back
  • * Weight loss or poor appetite
  • * Blood clots
  • * Persistent nausea or vomiting
  • * Jaundice or yellowing of the skin or the whites of the eyes

Early Stage Detection


This test is able to ‘catch’ pancreatic cancer signals circulating in a person’s blood that were once invisible.

This test was specifically designed for early stage detection. Scientists estimate that when pancreatic cancer is discovered early, the survival rate can increase dramatically.

There’s also evidence that there is a relatively long period of time between when the first signs of cellular changes appear in the pancreas and when the cancer spreads to other parts of the body. This means there is a substantial period of time and an important window of opportunity where pancreatic cancer can be potentially detected in the bloodstream and effectively treated.

That is why it is so important to understand if you or someone you know is at high risk to develop pancreatic cancer and to speak to your doctor about ordering this test.

Additional Information


The BT-Reveal Early Pancreatic Cancer Test is intended for use as a screening tool for at-risk individuals. A positive result does not guarantee the individual has cancer. For all positive results, additional follow-up imaging and other confirmatory tests are recommended. Common follow up testing includes CT Scans, MRI’s, Endoscopic Ultrasounds, or ERCP tests.

Breakthrough Genomics’s clinical laboratory in Irvine, California is certified in the U.S. under the Clinical Laboratory Improvements Amendments (CLIA) and by the College of American Pathologists (CAP) to perform high complexity clinical genomic tests. The BT-Reveal Early Pancreatic Cancer Test only requires a 10ml tube of blood that can be stored and transported at room temperature. The test is currently being offered as a Laboratory Developed Test (LDT) and as such surpasses the lab’s requirements needed to be able to safely provide the test to at-risk individuals.

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